A new eudesmane type sesquiterpene from cultivated Clerodendranthus spicatus in Hainan / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 95-99, 2019.
Article
in Zh
| WPRIM
| ID: wpr-771512
Responsible library:
WPRO
ABSTRACT
Six compounds were isolated from the aerial part of cultivated Clerodendranthus spicatus in Hainan with various chromatographic techniques,and their structures were determined as:1-dehydroxy-1-oxo-rupestrinol(1),N-trans-feruloyltyramine(2),methyl 3,4-dihydroxyphenyllactate(3),caffein acid(4),methyl caffeate(5) and ethyl caffeate(6),via analysis of physicochemical properties and spectroscopic evidence.Compound 1 was a new compound,while compounds 2 and 3 were isolated from C.spicatus for the first time.Biological activity results showed that compounds 2-4 exhibited α-glucosidase inhibitory activity with different inhibition ratio.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Pharmacology
/
Molecular Structure
/
Chemistry
/
China
/
Lamiaceae
/
Sesquiterpenes, Eudesmane
/
Phytochemicals
/
Glycoside Hydrolase Inhibitors
Country/Region as subject:
Asia
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2019
Document type:
Article